Other work showed that RPA70 overexpression in lymphoblastoid or glioblastoma cells negatively affected chromosomal stability and DSB repair, leading the authors to speculate that the overabundant RPA may sequester key binding partners [37]; however, a direct investigation of the hypothesis that overexpressed RPA highjacks helicases/translocases or other nuclear factors was not pursued. Here, RPA1 is linked to glioblastoma.