KRAS and colorectal carcinoma: To begin discerning what cellular programs might be involved in upregulating mutant KRAS protein expression, we analysed a broader panel of KRAS-mutant lung, pancreatic and CRC cell lines, and observed that lines that displayed high endogenous KRAS protein expression (KRAS-high lines) also tended to exhibit elevated expression of an ectopic KRAS transgene when compared to cell lines with low endogenous KRAS protein expression (KRAS-low lines) (Fig. 5c).