A previous report showed a significant degeneration in SCA3 in this area [6], however, our analysis also showed a negative correlation between GMV and the ataxia score, corroborating the functional relevance of this deterioration as shown by patients with lesions in this area, whom often show deficits in spontaneous initiation of movement and speech, as well as inability to suppress externally triggered motor subroutines [16]. This evidence concerns the gene ATXN3 and Ataxia.