TLR1, TLR2, TLR6, and TLR10 comprise the TLR2 subfamily, and TLR1, TLR2, TLR6, and TLR10 gene polymorphisms seem to play a role in susceptibility to asthma, atopic eczema, and allergic rhinitis10–12. The gene discussed is TLR1; the disease is atopic eczema.