a Quantification of MDSCs (CD11b+ Gr1+) in spleen, lymph node (LN), peripheral blood and tumor from wild type mice (WT) and 2cKO tumor bearing mice treated with DMSO (vehicle group) or with SCH58261(each group n = 6, Mean ± SEM, *, P < 0.05, ***, P < 0.001, ns = no significance, one way ANOVA with post Tukey test). Here, ITGAM is linked to neoplasm.