LGALS8 and posterior cortical atrophy: To evaluate whether Gal-8 is controlling these oncogenic parameters of human PCa cell lines, we transduced IGR-CaP1 and PC3 independently with two different lentivirus (LV) expressing GFP and a human Gal-8 shRNA (shGal-8.1 and shGal-8.2) or a control shRNA (shCtrl) containing a sequence that does not show nucleotide complementarity with any sequence found by BLAST in the human genome.