The expression of pro-fibrotic genes, such as PDGFB and PDGFC, and pro-inflammatory genes, such as interleukin (IL) 1β, IL6, CCL2, and CCL5, was increased in Ath+HF diet mice until 68 weeks, and their expression was repressed by peretinoin (Figure 2). This evidence concerns the gene CCL5 and hydrops fetalis.