For example, solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 (SLC34A2) induced chemoresistance in via SLC34A2-Bmi1-ABCC5 signaling in breast cancer cells [6]; cancer stem cells marker CD133+ contributed to resistance to therapy in hepatocellular carcinoma [7], suggesting that these two cellular processes are intimately linked. The gene discussed is SLC34A2; the disease is cancer.