Both led to loss of the MED12L gene (3q25.1) which shows strong similarity with MED12. Finally, the translocations t(5;11)(q13;q21) and t(6;11)(p23;q21) were reported in two uterine leiomyomas as the sole cytogenetic abnormality [26, 27]. This evidence concerns the gene MED12 and Uterine leiomyoma.