HSPD1 and diabetes mellitus: For HSPD1 rs2605039, diabetes significantly increased the risk of breast cancer among women with the GG genotype [OR (95%CI): 6.40 (2.29, 17.87)] but not the women with the GT/TT genotypes [1.16 (0.71, 1.89)], and the interaction was significant in a multiplicative model but not in an additive model (P values: 0.002 and 0.134, respectively) (Table 3).