Hyperglycemia exerts effects on carcinogenic process by concurring with a chronic inflammation state and an associated oxidative stress condition [11–13]; the former is accompanying with an elevated levels of inflammatory cytokines, such as interleukin-6 (IL-6) [14], whereas the latter may damage mitochondrial function that is closely related to heat shock protein 60 (hsp60, encoded by HSPD1) [15,16]. Here, HSPD1 is linked to Hyperglycemia.