Genotypes of FTO rs3751812, IL-6 rs1800796 and HSPD1 rs2605039 were equally distributed in the cases and controls and consequently not significantly associated with breast cancer risk [ORs and 95%CIs of dominant effects: 0.91 (0.75, 1.10), 1.07 (0.91, 1.26) and 0.96 (0.80, 1.14), respectively] (Table 2), and these findings did not change materially with menopausal status (S2 Table). Here, FTO is linked to breast cancer.