Development of just a single ERBB3 peptide vaccine can be found in the literature [181] however, peptide vaccines targeting ERBB1 [203, 204], ERBB2 [205–207] or both ERBB1/2 [208] including monoclonal antibody against tyrosine related protein 1 (TRP-1) and altered peptide sequence to gp100 for mouse melanoma [209] all show promise. Here, EGFR is linked to melanoma.