We performed WES on 48 women with OVCA suspected to have inherited cancer predisposition, yet, were previously tested and found negative for known pathogenic mutations in either BRCA1 or BRCA2. In doing so, we discovered pathogenic variants in ATM (n = 2) and FANCM (n = 1), genes currently associated with breast cancer but not OVCA, as well as in a gene recently implicated in hereditary ovarian cancer risk, RAD51D (n = 2). Here, BRCA2 is linked to cancer.