TNFRSF11B and osteoporosis: Limited evidence suggest that moxibustion plus anti-osteoporosis medicine may be more effective in reducing the pain (VAS scores average changed 2 scores between groups, 4 trials), increasing the BMD of femoral neck (average changed 0.4 g/cm2 between groups, 3 trials), and improving the level of BGP, OPG and BALP (2 trials) compared with anti-osteoporosis medicine alone.