PPARGC1A and type 2 diabetes mellitus: A meta-analysis by Yang et al[29] indicated that the polymorphisms of Gly482Ser (rs8192678) and Thr394Thr (rs2970847) in the PPARGC1A gene were significantly associated with the risk of T2DM, especially in the Indian population, with OR values (95% CI) of 1.19(1.05–1.34) and 1.33(1.34–1.70), respectively.