Although the number of studies that include tumor analyses of EMT markers is considerable, most common alterations studied within human tumor samples are related to the loss or aberrant expression of proteins required to maintain the epithelial phenotype and usually involved in cell–cell adhesion (Steinestel et al., 2014), being E‐cadherin one of the strongest markers routinely used in the clinic for cancer diagnosis or progression (Pasquier et al., 2015). This evidence concerns the gene CDH1 and cancer.