(2015) is that the deletion of Snail1 or Twist1 might be compensated by other EMT‐TFs as has been described in cell culture models (Diaz‐Lopez et al., 2015) or, alternatively, that EMT‐TFs expression is tumor specific, being Snail1 or Twist1 dispensable for pancreatic cancer metastasis. This evidence concerns the gene TWIST1 and pancreatic neoplasm.