TGFB1 and neoplasm: The chemokine CXCL12 was found to be upregulated in the lymphatic endothelium of draining lymph nodes, alongside migrating tumor cells expressing the CXCR4 receptor (Hirakawa et al., 2009), and this system is linked to TGF‐β‐induced EMT (Bertran et al., 2009; Taki et al., 2008).