WNT10A and ectodermal dysplasia syndrome: WNT10A is the most commonly mutated gene in human non-syndromic selective agenesis of permanent teeth1, 2 and WNT10A mutations are also associated with the ectodermal dysplasia syndromes Odonto-onycho-dermal dysplasia (OMIM #257980) and Schöpf–Schulz–Passarge syndrome (OMIM #224750)3.