For instance, the intracellular Lewy bodies containing aggregated α-synuclein, the inclusions of aggregated huntingtin protein and the inclusions of copper–zinc superoxide dismutase (SOD1) mutants are histological hallmarks found in Parkinson's disease (PD), Huntington's disease and amyotrophic lateral sclerosis, respectively. The gene discussed is SOD1; the disease is Parkinson disease.