To assess the Dnm2 knockdown efficacy of selected ASOs in vivo and to potentially rescue the myotubular myopathy phenotype, 20 μg of ASO#1, #2 or #3 were injected weekly into the right tibialis anterior (TA) of 3-week-old WT or Mtm1KO mice and the same dose of control ASO was injected into contralateral limbs. This evidence concerns the gene DNM2 and myopathy.