With regard to that, a mutation in the FOXP3 human gene is responsible for the human syndrome known as immunodysregulation, polyendocrinopathy, and enteropathy X-linked syndrome (IPEX), or X-linked autoimmunity and allergic dysregulation syndrome (XLAAD), equivalent to the murine syndrome known as Scurfy (10, 15–17). The gene discussed is FOXP3; the disease is immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.