TSPO and schizophrenia: Furthermore, correlating in vivo positron emission tomography imaging of MAP using TSPO C11-PK11195 (4, 7) with serum biomarkers of vascular endothelial dysfunction and BBB breakdown may shed additional light on the role of neuroinflammation-related cerebral microvascular endotheliopathy and BBB hyperpermeability in the pathophysiology of schizophrenia.