GLRA2 and autism spectrum disorder: Consistent with these findings, microdeletions and missense mutations in the human GlyR α2 subunit gene (GLRA2), which is located on the X-chromosome, have been associated with rare cases of autism spectrum disorder (ASD) in the hemizygous state in males (Pinto et al., 2010; Piton et al., 2011; Iossifov et al., 2014; Pilorge et al., 2016).