Considering that CNBP is expressed at higher levels than DMPK in muscles, and that expanded alleles tend to carry more CTG repeats, as well as the fact that MBNL proteins have higher affinity for CCUG repeats than for CUG RNA, DM2 symptoms should be more severe, rather than milder, than DM1. The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.