Indeed, several studies have reported that DM2 individuals tend to carry significantly more (75 to approximately 11,000, with a mean of 5,000 CCTG) repeats in mutant alleles compared to patients with CTG expansions (classic DM1 range is 100–1000 repeats)3 and, according to different sources CNBP is 4 to 8-fold more expressed in human muscles than the DMPK gene27–29. This evidence concerns the gene DMPK and myotonic dystrophy type 1.