The univariate analysis demonstrated that age, diabetes, hypertension, C-peptide levels, uric acid levels, eGFRs, TC levels, triglyceride (TG) levels, ALT levels, bilirubin (t) levels, high sensitivity C-reactive protein (Hs-CRP) levels and INRs were associated with baseline RBP4 levels, whereas the multivariate analysis confirmed that the baseline eGFRs, TC levels and INRs were independently associated with the baseline RBP4 levels. The gene discussed is CRP; the disease is Hypertension.