Accordingly, we analyse the cytokine expression changes (more than 1.5 log2, 2.8 fold, p < 0.05, t-test) between No take and Take tumours and found a large series of chemokine/cytokine overexpressed in the No take samples, among them IFNG, CXCL13, CXCl9, CXCl11, CXCL10 and CCL5 (Fig. 6b). This evidence concerns the gene CXCL9 and neoplasm.