INS and type 2 diabetes mellitus: In conclusion, the data from the lipid substudy of the BIL Phase 3 program in insulin-treated cohorts of both type 1 and type 2 diabetes, with multiple measures of soluble biomarkers related to lipid/lipoprotein concentrations, provide a unique and extensive database on the effects of insulin glargine and an investigational hepato-preferential insulin (BIL).