Additionally, chrysin potentiates the apoptotic effect of TRAIL in CNE1 nasopharyngeal, HeLa cervical, A549 lung and HCT116 colon cancer cells, and apigenin augments TRAIL-mediated apoptosis in Jurkat leukemia T cells, HeLa cervical, DLD1 colon and DU145 prostate cancer cells [52,53,54]. This evidence concerns the gene TNFSF10 and malignant colon neoplasm.