CCL2 and neoplasm: The CCL2 mRNA and protein expression were significantly reduced by l-CDL treatment at the dose of 10 mg/kg or 20 mg/kg group in comparison with tumor group (p < 0.05, p < 0.01) (Figure 5A,C), and possessed stronger ability than O&A group and l-THP group in decreasing the expression of mRNA for CCL2 levels (Figure 5A).