Several of its targets include disease-associated RBPs, such as TAR DNA-binding protein 43 (TDP-43; ALS), CCR4-NOT transcription complex subunit 1 (CNOT1; iritis), Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNPA2B1; inclusion body myopathy), ELAV Like neuron-specific RNA-binding protein 2 (ELAVL2; Parkinson’s disease) and PABP1 (oculopharyngeal muscular dystrophy) [20]. The gene discussed is TARDBP; the disease is Parkinson disease.