MiR-98 was observed to be downregulated in various cancer cell lines, and its overexpression inhibited hepatocellular carcinoma (HCC) cell proliferation, migration, and invasion in vitro [50] via suppression of NF-κB p65 nuclear translocation and MMP9 [51] and Sal-like protein 4 expression in HCC and NSCLC cells [15,52]. This evidence concerns the gene MMP9 and cancer.