EGFR and squamous cell carcinoma: Similarly, Oliveira et al. utilized the same photosensitizer to deliver EGFR siRNA in a human epidermoid carcinoma cell line (A431 cell line) and found a 10-fold increase in the knockdown of EGFR protein expression after light irradiation at 375–450 nm with 13 mW/cm2 power [134].