Furthermore, the corresponding region in humans, located 1.7 Mb downstream of MYC, has previously been identified to undergo focal amplifications in acute myeloid leukemia (AML) and is hyperacetylated in T-cell leukemias and chronic myelogenous leukemia [125,126,127,128,129,130]. The gene discussed is MYC; the disease is acute myeloid leukemia.