We find association of three intronic variants in the genes ARHGAP15 (Rho GTPase-activating protein 15) and COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase) with diverticular disease and in FAM155A (family with sequence similarity 155A) with diverticulitis. Here, NALF1 is linked to Colonic diverticula.