CDKN2C and plasma cell myeloma: Amongst Myeloma XI trial patients, homozygous deletion of CDKN2C (1p32), BIRC2/BIRC3 (11q22) and amplification of CKS1B (1q21) and MYC (8q24) were the commonest focal homozygous copy number changes, which were seen at similar frequencies to those previously reported (Table 1).15