PLAT and Stroke: To provide acute stroke care in the early stages, current recommendations from Level-1 evidence for best practice include (1) stroke care in a specialist stroke unit [18, 19], (2) thrombolytic therapy with intravenous tissue plasminogen activator (t-PA) within 4.5 h of an acute ischemic stroke [20–22], (3) aspirin administration within 48 h of acute ischemic stroke onset [23–25] and (4) decompressive surgery if required within 48 h of stroke onset [26, 27].