Therefore, our results obtained in humans at the end stage, i.e., postmortem, do not support the epidemiological, clinical, or experimental data suggesting that a causative relationship exists between DM and AD, i.e., misfolded protein IAPP acts as a seed for misfolding of Aβ, HPτ, and αS or vice versa [19]. This evidence concerns the gene IAPP and Alzheimer disease.