The results of western blot revealed that the high expressions of NLRP3/ASC/IL-1β pathway-related proteins in AD rats were effectively inhibited by EX (2 g/kg, 6 g/kg) to different degrees, indicating the impact of NLRP3 on AD and the effectiveness of EX in the treatment of AD rats induced by Aβ1-42 administration. Here, NLRP3 is linked to Alzheimer disease.