Data after false discovery rate (FDR) adjustment at q=0.05 of features showed136 for positive and 350 significant features for negative ionization mode in NHL patients aswell as 262 for positive and 98 features for negative ionization mode in myeloma patients.Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis determined thatpathways such as steroid hormone biosynthesis, ABC transporters, and arginine and prolinemetabolism were affected in NHL patients. This evidence concerns the gene ABCG2 and non-Hodgkin lymphoma.