NQO1 and pancreatic neoplasm: In recent years, NAD(P)H:quinone oxidoreductase-1 (NQO1, EC 1.6.99.2) is a flavoprotein overexpressed up to 5- to 200-fold compared to normal adjacent tissue in various solid tumors, including cancers of the pancreas, lung, prostate and breast4–6, in terms of drug development.