The IHC staining revealed increased expression of E-cadherin, and decreased expression of Ki-67, Vimentin, snail, phosphorylation of Akt, S6, and 4EBP1 in the high-dose β-lap-treated tumour group compared with the other groups (Fig. 7E, Supplemental Fig. 4). Here, MKI67 is linked to neoplasm.