The IHC staining revealed increased expression of E-cadherin, and decreased expression of Ki-67, Vimentin, snail, phosphorylation of Akt, S6, and 4EBP1 in the high-dose β-lap-treated tumour group compared with the other groups (Fig. 7E, Supplemental Fig. 4). The gene discussed is VIM; the disease is neoplasm.