CDKN2A and Miyoshi myopathy: Previously we have shown using our MexTAg transgenic mouse model [24] that the presence of exogenous SV40 large T antigen (Tag) performs a similar molecular role as Cdkn2a loss [21] In both the wild type and MexTAg model, asbestos-induced MM was not associated with reduced expression of other genes commonly down-regulated in human MM [21].