Four samples (10%) were negative for APCprotein expression in adenocarcinoma and 36 (90%) werepositive (Table 3, Fig. 1).In gastric tumour Stage III, 7.5% of the samples showed negative protein expression.After performing the Fisher exact test, the APC expression was not significantlycorrelated with the Stages of gastric cancer (p = 0.077).APC immunoreactivity showedpositive expression of the protein in the stage I (47.5%), stage II (25%) and stage III (17.5%) gastric adenocarcinoma and Stage III (7.5%) and stage IV (2.5%) showed negative expression of the protein. The gene discussed is APC; the disease is gastric neoplasm.