The model combining the 3 SNPs associated with pancreatitis (i.e. rs72755233 in ADAMTS17, rs3809849 in MYBBP1A and rs9908032 in SPECC1) was also replicated in the validation cohort (OR = 2.2; 95% CI, 1.1-4.6; P = 0.02, Figure 5d), as also was the comprehensive model with the five variants (OR = 2.6; 95% CI, 1.3-5.4; P = 0.005, Supplemental Figure S1). This evidence concerns the gene MYBBP1A and pancreatitis.