TNF and head and neck squamous cell carcinoma: However, these responses were less prominent than the responses by lymph node cells of control mice (IL-17 responses to both premalignant and HNSCC: p < 0.01 at each of the time points; TNF-α responses to lesion or HNSCC: p < 0.01 at weeks 1 and 3, and p < 0.05 at week 5).