In addition, the available data exhibited that IL-31 contributed to atopic dermatitis [17, 18], nonatopic eczema [19], systemic lupus erythematosus (SLE) [20], asthma [21], inflammatory bowel disease (IBD) [14], familial primary cutaneous amyloidosis [22], Kawasaki disease [23], hepatitis B virus liver failure [24], and allergic rhinitis [25]. Here, IL31 is linked to asthma.