H2AX and metabolic syndrome: After the adjustment for age, sex, cigarette smoking and alcohol consumption, and percentage and mean fluorescence intensity (MFI) of phosphorylated H2AX were still significantly higher in the MetS risk carriers (n = 17) than in super healthy people (n = 18) (for percentage, super healthy: 3.44 ± 0.53% versus MetS risk: 5.34 ± 0.70%; for MFI, super healthy: 109.1 ± 21.1 versus MetS risk: 205.9 ± 39.3) (p < 0.05 for all) (Figure 1(a)).