Previously, there were two meta-analyses that revealed the GSTP1 IIe105Val, GSTM1 null genetic polymorphisms and the efficacy of platinum-based chemotherapy in NSCLC patients and no meta-analysis about GSTT1 null genetic polymorphisms and the efficacy of platinum-based chemotherapy in NSCLC patients17, 40. This evidence concerns the gene GSTP1 and non-small cell lung carcinoma.