CD8A and infection: In addition, suppression of TMEM20 expression by infection with small interfering RNA targeting TMEM20 (siTMEM20) decreased intracellular Ca2+ levels in naïve mir-150−/− CD8+ T cells, indicating that the balance between TMEM20 and miR-150 regulates intracellular Ca2+ levels in naïve CD8+ T cells (Fig. 6e).