Additionally, retro-miR-150 infection of mir-150−/− CD8+ T cells reduced expression of anergy-related genes Cbl-b, Egr2, and p27 and increased the expression of activation-induced molecules granzyme B, cyclin B1, and Blimp1 following anti-CD3/CD28 stimulation (Fig. 6c,d). Here, CD28 is linked to infection.