CDH2 and neoplasm: However, our data showed that the level of N-cadherin expression in TAN tissues was higher than that in the tumor (p<0001; Table 1), indicating that N-cadherin may mediate a less stable and more dynamic form of cell-cell adhesion, which may allow both attachment and detachment of individual cells from the primary tumor and selective association with tissues such as the stroma or endothelium in TAN tissues [29].