2) Immunohistochemical phenotype: there were 71 cases of Her-2 (-) breast cancer (42.5%), 37 cases of Her-2 (+) breast cancer (22.1%), 26 cases of Her-2 (++) breast cancer (15.6%) and 33 cases of Her-2 (+++) breast cancer (19.8%). Here, ERBB2 is linked to breast cancer.