However, it is noteworthy that among these three patients, one was diagnosed with a colon cancer 18 months after inclusion, although his FDG-PET/CT at inclusion was clearly negative (which was confirmed by post-hoc repeated interpretation); another patient was diagnosed with a prostate cancer (PSA 6.2) although his FDG-PET/CT was equivocal at the level of the lung and the stomach; the last patient was also diagnosed with prostate cancer, his FDG-PET/CT was equivocal in the prostatic bed and his PSA level was 8.1. Here, PROS1 is linked to malignant colon neoplasm.